What's The Harm?
Posted: Wed Apr 16, 2008 6:44 am
One of the most common responses you hear from supplement users, is that even if there is not any benefit, what is the harm in using them. Maybe they just offer come extra insurance, and/or protection.
Apparently not. And, this is not the first study to show this.
But, this one just came out from the Cochrance Group, which is one of the most respected groups out there for reviewing medical research.
In Health
Jeff
Vitamins 'may shorten your life'
Research has suggested vitamin supplements do not extend life and could even lead to a premature death.
A review of 67 studies found "no convincing evidence" that antioxidant supplements cut the risk of dying.
Scientists at Copenhagen University said vitamins A and E could interfere with the body's natural defences.
"Even more, beta-carotene, vitamin A, and vitamin E seem to increase mortality," according to the review by the respected Cochrane Collaboration.
The research involved selecting various studies from 817 on beta-carotene, vitamin A, vitamin C, vitamin E, and selenium which the team felt were the most likely to fairly reflect the benefits of the supplements.
It has been thought that these supplements may be able to prevent damage to the body's tissues called "oxidative stress" by eliminating the molecules called "free radicals" which are said to cause it.
This damage has been implicated in several major diseases including cancer and heart disease.
'Just eat well'
The trials involved 233,000 people who were either sick or were healthy and taking supplements for disease prevention.
After various factors were taken into account and a further 20 studies excluded, the researchers linked vitamin A supplements to a 16% increased risk of dying, beta-carotene to a 7% increased risk and vitamin E to a 4% increased risk.
Vitamin C did not appear to have any effect one way or the other, and the team said more work was needed into this supplement - as well as into selenium.
In conclusion, "we found no evidence to support antioxidant supplements for primary or secondary prevention," they said.
It was unclear exactly why the supplements could have this effect, but the team speculated that they could interfere with how the body works: beta-carotene, for instance, is thought to change the way a body uses fats.
The Department of Health said people should try to get the vitamins they need from their diet, and avoid taking large doses of supplements - a market which is worth over £330m in the UK.
"There is a need to exercise caution in the use of high doses of purified supplements of vitamins, including antioxidant vitamins, and minerals," a spokesperson said.
"Their impact on long-term health may not have been fully established and they cannot be assumed to be without risk."
Apparently not. And, this is not the first study to show this.
But, this one just came out from the Cochrance Group, which is one of the most respected groups out there for reviewing medical research.
In Health
Jeff
Vitamins 'may shorten your life'
Research has suggested vitamin supplements do not extend life and could even lead to a premature death.
A review of 67 studies found "no convincing evidence" that antioxidant supplements cut the risk of dying.
Scientists at Copenhagen University said vitamins A and E could interfere with the body's natural defences.
"Even more, beta-carotene, vitamin A, and vitamin E seem to increase mortality," according to the review by the respected Cochrane Collaboration.
The research involved selecting various studies from 817 on beta-carotene, vitamin A, vitamin C, vitamin E, and selenium which the team felt were the most likely to fairly reflect the benefits of the supplements.
It has been thought that these supplements may be able to prevent damage to the body's tissues called "oxidative stress" by eliminating the molecules called "free radicals" which are said to cause it.
This damage has been implicated in several major diseases including cancer and heart disease.
'Just eat well'
The trials involved 233,000 people who were either sick or were healthy and taking supplements for disease prevention.
After various factors were taken into account and a further 20 studies excluded, the researchers linked vitamin A supplements to a 16% increased risk of dying, beta-carotene to a 7% increased risk and vitamin E to a 4% increased risk.
Vitamin C did not appear to have any effect one way or the other, and the team said more work was needed into this supplement - as well as into selenium.
In conclusion, "we found no evidence to support antioxidant supplements for primary or secondary prevention," they said.
It was unclear exactly why the supplements could have this effect, but the team speculated that they could interfere with how the body works: beta-carotene, for instance, is thought to change the way a body uses fats.
The Department of Health said people should try to get the vitamins they need from their diet, and avoid taking large doses of supplements - a market which is worth over £330m in the UK.
"There is a need to exercise caution in the use of high doses of purified supplements of vitamins, including antioxidant vitamins, and minerals," a spokesperson said.
"Their impact on long-term health may not have been fully established and they cannot be assumed to be without risk."