Coffee, Acrylamides, Cancer and You

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Coffee, Acrylamides, Cancer and You

Postby JeffN » Sat Mar 31, 2018 7:23 am

In regard to the latest news on Coffee, Acyrlamides, Cancer and you.

First, some past discussions/posts on Coffee

Coffee
viewtopic.php?f=22&t=5696

Coffee vs Tea
viewtopic.php?f=22&t=7608

Re: A second newbie question concerning coffee.
viewtopic.php?f=22&t=5956&p=40962&#p40962

Can a person be allergic to coffee
viewtopic.php?f=22&t=6835

Coffee, Bowel Movements and Is Decaf Caffeine Free
viewtopic.php?f=22&t=9794&p=73893#p73893


On Acrylamides

Acrylamide from baking -- should I be concerned?
viewtopic.php?f=22&t=7057

Acrylamides in Grain Beverages
viewtopic.php?f=22&t=8893


Dr McDougall on Acrylamides
https://www.drmcdougall.com/misc/2005nl ... lamide.htm

https://www.drmcdougall.com/misc/2002nl ... lamide.htm



On the current issue of Coffee and Acrylamides

From the WHO IARC

IARC Monographs evaluate drinking coffee, maté, and very hot beverages
June 15, 2016
https://www.iarc.fr/en/media-centre/pr/ ... r244_E.pdf

The Working Group found no conclusive evidence for a carcinogenic effect of drinking coffee.


Q&A on Monographs Volume 116: Coffee, maté, and very hot beverages
https://www.iarc.fr/en/media-centre/iar ... Vol116.pdf

10.Does the IARC classification mean that coffee is safe in terms of a potential link to cancer? A Group 3 evaluation does not mean that a substance has been proven to be safe. It means that the existing scientific data do not enable a conclusion to be made about whether it causes cancer. While this was the case for coffee overall, it was possible to conclude that coffee is unlikely to cause certain cancers, including cancers of the breast, prostate, and pancreas. Reduced risks were seen for cancers of the liver and uterine endometrium. For more than 20 other cancers, the evidence was inadequate to enable a conclusion to be made.

Also, California Proposition 65 requires cancer warnings for any product that contains more than 0.2 mcg of acrylamide per day. The EPA permits up to 140 mcg per day before a warning is required

While coffee is not a health food and I don't recommend it, as I said in my Coffee vs Tea post..

viewtopic.php?f=22&t=7608

Out of the two drinks, tea is clearly the better "choice" if you were looking to choose between the two. If you were to choose coffee, keep the intake below 2-3 6 oz cups a day, have it black, and make sure it is paper filtered.

In Health
Jeff
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Re: Coffee, Acrylamides, Cancer and You

Postby JeffN » Wed Apr 04, 2018 7:52 am

For the coffee drinker, the following tips that will help reduce acrylamides.

Coffee in Health and Disease Prevention 2015
Chapter 24 – Factors Affecting Acrylamide Levels in Coffee Beverages
2015, Pages 217–224
Cristina M.D. Soares1, ∗, Rita C. Alves2, 3, ∗, M. Beatriz P.P. Oliveira2

https://doi.org/10.1016/B978-0-12-409517-5.00024-3

- Choose coffee made from Arabica beans, which contain lower amounts of asparagine than Robusta beans. However, be aware that this won't guarantee lower acrylamide, since amounts are also affected by roasting time, temperature, etc.

- Store coffee before using for longer periods of time. Acrylamide levels in commercial ground coffee and beans decrease over time when stored in their original container. Reductions of 40—60% have been reported in coffees stored at room temperature over a period of 6—12 months.

- Plunger pot and filtered, drip brew coffee preparation typically results in less acrylamide than coffee prepared by decoction (such as Turkish coffee) and pressure preparation (French press, expresso).

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Re: Coffee, Acrylamides, Cancer and You

Postby JeffN » Wed Apr 11, 2018 7:24 am

To get a better sense of how much acrylamide is in some foods (and how this compares to the EPA's limit of 140 mcg of acrylamide per day), here are some examples

Food
Serving size
Acrylamide per serving (mcg)


French fries, oven-baked
2.5 ounces (about 12 fries, depending on size) 48.8 mcg

Prune juice
5 ounces
30 mcg to 100 mcg

French fries, restaurants
2.5 ounces (about 12 fries, depending on size)
28.3 mcg

Potato chips
1 ounce (about 15 chips)
17.9 mcg

Canned black olives
5 olives
3.2 to 8 mcg

Breakfast cereal
2 ounces (1/4 cup)
6.6 mcg

Brewed coffee
8 ounces
1.9 mcg

California-style green ripe olives
5 olives
1 mcg

Roasted Kasha
45 mg (dry) serving
.5 mcg

Acrylamide Intake through Diet and Human Cancer Risk
Mucci, J. Agric. Food Chem. 56, 15, 6013-6019
DOI: 10.1021/jf703747b

Review of Methods for the Reduction of Dietary Content and Toxicity of Acrylamide
Friedman, J Agric Food Chem 2008
https://pubs.acs.org/doi/abs/10.1021/jf0730486

Formation of acrylamide at temperatures lower than 100°C: the case of prunes and a model study.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011
Jun;28(6):726-30.
doi: 10.1080/19440049.2010.535217.

Influence of California-style black ripe olive processing on the formation of acrylamide.
J Agric Food Chem. 2014 Aug 27;62(34):8716-21.
doi: 10.1021/jf5022829. Epub 2014 Aug 15.

Effect of roasting time of buckwheat groats on the formation of Maillard reaction products and antioxidant capacity
Food Chemistry
Volume 196, 1 April 2016, Pages 355-358
https://www.sciencedirect.com/science/a ... 4615014077
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Re: Coffee, Acrylamides, Cancer and You

Postby JeffN » Sat Oct 24, 2020 9:37 am

Not just of relevance to acrylamide and cancer but to the whole issue of looking at nutrients in isolation. Remember, whole foods over isolated nutrients, and dietary patterns over individual whole foods.

https://www.drmcdougall.com/forums/view ... 22&t=44163


The Coffee-Acrylamide Apparent Paradox: An Example of Why the Health Impact of a Specific Compound in a Complex Mixture Should Not Be Evaluated in Isolation.
Nutrients. 2020 Oct 14;12(10):E3141. doi: 10.3390/nu12103141.
PMID: 33066651 Free article.

Abstract

The health implications of acrylamide in food are a matter of concern based on toxicological studies in rodents, which showed that doses of acrylamide more than 100 times higher than those estimated to result from dietary exposure in humans are carcinogenic; however, the cancer types reported in rodents are species-specific, and whether these results can be extrapolated to humans is still in question. In fact, human epidemiological studies revealed a general lack of association between dietary acrylamide exposure and the incidence of different cancer types. Even occupational exposure to acrylamide, resulting in acrylamide exposure nearly 10 times higher than dietary exposure, did not increase tumor occurrence. Furthermore, the consumption of coffee, which is a main contributor of dietary acrylamide exposure, actually decreases the overall incidence of cancer in humans and afford global health benefits, increasing both lifespan and healthspan on ageing. This paradox clearly illustrates the risk of evaluating an individual molecule independently of its complete food matrix, which may have other components that completely override the effects of the considered molecule.
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