Common heartburn drugs linked with kidney disease

[soul food]

http://www.cbsnews.com/news/common-hear ... y-disease/

Common heartburn drugs linked with kidney disease

by DENNIS THOMPSON HEALTHDAY January 11, 2016, 2:27 PM

A type of heartburn medication called proton pump inhibitors may be linked to long-term kidney damage, a new study suggests.

Prilosec, Nexium and Prevacid belong to this class of drugs, which treat heartburn and acid reflux by lowering the amount of acid produced by the stomach.

People who use proton pump inhibitors (PPIs) have a 20 percent to 50 percent higher risk of chronic kidney disease compared with nonusers, said lead author Dr. Morgan Grams, an assistant professor of epidemiology at Johns Hopkins University in Baltimore.

The study was published Jan. 11 in JAMA Internal Medicine.

I am glad I made the huge effort to change my diet and get off Nexium.

soul food

[pundit999]

These drugs are poisons. There were reports earlier that they dissolve your bones if you are on them for longer than a year.

I am saddened that so many drugs are on market that are actually bad for you. And they find out that are so only after the pharmaceutical industry has made most money off of them: after the patent has expired.

Next shoe to fall: statins. I can almost bet!

[Debbie]

I took them until about 2 weeks ago or so. I had suspected H. Pylori, which I wasn't able to get tested until after 5 days of being in the hospital, and ended up in the hospital with an emergency gallbladder removal...stayed 6 days with round the clock iv antibiotics for infected bile ducts. Went from 20mgs of omeprazole, to 40mgs!! I thought this is nuts. Because they are capsules, there was no real way to taper them down....The capsules are 20mgs and was supposed to take 2, so I tapered to 1 then every other day...sort of, I just kind of quit. While I had some off and on discomfort, eating helped that, but yesterday was the first day I had significant discomfort. Sadly I took a swig of maalox and that seemed to help a little. Also laying on my left side helps. But my pain is more in my mid back/abdomen than my esophagus....but it radiates. Anyway, I am glad I stopped taking this drug and hope my discomfort goes away soon.

[bbq]

http://nutritionfacts.org/video/diet-and-gerd-acid-reflux-heartburn/

Bottomline, GERD is common; its burdens are enormous. It relapses frequently and can cause bleeding and strictures, not to mention a deadly cancer. The mainstay of treatment is the proton pump inhibitor drugs, which rake in billions of dollars. We spend four billion dollars on Nexium alone, three billion on Prevacid, two billion on Protonix, one billion on Aciphex. But they can cause nutrient deficiencies, increase the risk for pneumonia, food poisoning, and bone fractures.

Acid reflux drug may cause heart disease, study suggests
https://www.sciencedaily.com/releases/2013/07/130710114225.htm

Proton pump inhibitors decrease diversity in gut microbiome, increase risk for complications
https://www.sciencedaily.com/releases/2014/11/141125074656.htm

Acid reflux medications may increase kidney disease risk
https://www.sciencedaily.com/releases/2015/10/151027100724.htm

Proton pump inhibitors associated with risk of chronic kidney disease
https://www.sciencedaily.com/releases/2016/01/160111135035.htm

Commonly used reflux, ulcer medication may cause serious kidney damage
https://www.sciencedaily.com/releases/2016/04/160414214855.htm

Popular heartburn medication may increase ischemic stroke risk
https://www.sciencedaily.com/releases/2016/11/161115163944.htm

Acid suppression medications linked to serious gastrointestinal infections
https://www.sciencedaily.com/releases/2017/01/170105082813.htm

Popular heartburn drugs linked to gradual yet 'silent' kidney damage
https://www.sciencedaily.com/releases/2017/02/170222082252.htm
https://medicine.wustl.edu/news/popular-heartburn-drugs-linked-gradual-yet-silent-kidney-damage/

Unexpected Effect of Proton Pump Inhibitors
http://circ.ahajournals.org/content/128/8/845

Prolonged use of a proton pump inhibitor reduces microbial diversity: implications for Clostridium difficile susceptibility
https://microbiomejournal.biomedcentral.com/articles/10.1186/2049-2618-2-42

Proton pump inhibitors are associated with increased risk of development of chronic kidney disease
https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-016-0325-4

Acid-suppression medications and bacterial gastroenteritis: a population-based cohort study
http://sci-hub.cc/10.1111/bcp.13205
http://onlinelibrary.wiley.com/doi/10.1111/bcp.13205/abstract

Adverse Effects Associated With Proton Pump Inhibitors
http://sci-hub.cc/10.1001/jamainternmed.2015.7927
http://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2481153

Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease
http://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2481157

Proton Pump Inhibitors and Risk of Incident CKD and Progression to ESRD
http://jasn.asnjournals.org/content/27/10/3153

Long-term kidney outcomes among users of proton pump inhibitors without intervening acute kidney injury
http://www.kidney-international.org/article/S0085-2538(17)30005-4/fulltext

[mommyfostej]

I took them for years on and off but my GI MD took me off due to higher risk of Alzheimer's Disease so they're finding other risks too... Thankfully, since going on this WOE, I'm doing much better with Gerd/reflux