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Excess ectopic fat storage is linked to type 2 diabetes. The importance of dietary fat composition for ectopic fat storage in humans is unknown. We investigated liver fat accumulation and body composition during overfeeding saturated fatty acids (SFAs) or polyunsaturated fatty acids (PUFAs). LIPOGAIN was a double-blind, parallel-group, randomized trial. Thirty-nine young and normal-weight individuals were overfed muffins high in SFAs (palm oil) or n-6 PUFAs (sunflower oil) for 7 weeks. Liver fat, visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue (SAT), total adipose tissue, pancreatic fat, and lean tissue were assessed by magnetic resonance imaging. Transcriptomics were performed in SAT. Both groups gained similar weight. SFAs, however, markedly increased liver fat compared with PUFAs and caused a twofold larger increase in VAT than PUFAs. Conversely, PUFAs caused a nearly threefold larger increase in lean tissue than SFAs. Increase in liver fat directly correlated with changes in plasma SFAs and inversely with PUFAs. Genes involved in regulating energy dissipation, insulin resistance, body composition, and fat-cell differentiation in SAT were differentially regulated between diets, and associated with increased PUFAs in SAT. In conclusion, overeating SFAs promotes hepatic and visceral fat storage, whereas excess energy from PUFAs may instead promote lean tissue in healthy humans.
OBJECTIVE: Obesity is associated with increased metabolic and cardiovascular risk. The ectopic fat hypothesis suggests that subcutaneous fat may be protective, but this theory has yet to be fully explored.
CONCLUSIONS: Although adiposity increases the absolute risk of metabolic and cardiovascular disease, abdominal subcutaneous fat is not associated with a linear increase in the prevalence of all risk factors among the obese, most notably, high triglycerides.
I don't know what the pathways or slogans are except that all excess calories are ultimately converted into fat and stored. If I over eat no matter what it is, I immediately start to add a pot belly and increase insulin resistance. There is this and that research study, thermogenesis, yadayada, and then there is my daily experience. If I add more than my usual amount of starch calories, say by eating some more calorie dense options like bread or pasta, it only takes a few days before my abdominal "pinch an inch" is obviously, visually thicker, my entire abdomen gets rounder and sticks out a little more, and the numbers on my blood glucose meter start climbing.chris. wrote:What are the pathways through which visceral fat could be generated from a starch-based calorie surplus, though? As long as one isn't eating any overt fats during overfeeding, how can fat be stored around the organs?
Entenmann's...Mmmmmmmmmm.... (Where's that Homer Simpson smilie when I really need it???)Jumpstart wrote:Wow, first overeating starch won't make you fat and now overeating oils will simply grown you more muscle. It's truly a miracle that anyone in the America has even one excess pound of fat anywhere on their body. You kind of wonder how it's possible that junk food vegans gets fat since they don't eat any saturated fat. And since they eat a lot of olive oils you'd expect them to have the muscles of Arnold. Where do you people find these garbage studies and WHY are you looking? Isn't what Dr. McDougall tells you enough?
Jumpstart wrote:Wow, first overeating starch won't make you fat and now overeating oils will simply grown you more muscle. It's truly a miracle that anyone in the America has even one excess pound of fat anywhere on their body. You kind of wonder how it's possible that junk food vegans gets fat since they don't eat any saturated fat. And since they eat a lot of olive oils you'd expect them to have the muscles of Arnold. Where do you people find these garbage studies and WHY are you looking? Isn't what Dr. McDougall tells you enough?
dteresa wrote:I could pick an infallible guru whose every word is derived from golden tablets from on high and blindfold myself, put in ear plugs, and refuse to learn anything new or anything from anyone other than my guru. Or I could acknowledge that I have an intellectual part of my being and continue to read, to learn to evaluate ask questions and make my own decisions. Or not. Whatever floats your boat.
didi
chris. wrote:I'm wondering if the McDougall diet alone can get rid of visceral fat. Sources I've read seem to say vigorous exercise is needed to get rid of visceral fat (but I'm sure these sources don't factor in a complete lifestyle change like WFPB). It makes more sense that the shedding of stubborn subcutaneous fat requires vigorous exercise.
chris. wrote:My T levels shot down and I became pretty much emaciated when potatoes were my primary starch, likely because I was so satiated by the potatoes that I couldn't get any more food down, thus leading to an unintentional calorie deficit.
viv wrote:Did your visceral fat go away when you became "emaciated" eating potatoes as your main starch?
chris. wrote:Coconut oil? Dark chocolate? Macadamia nuts? There are plenty of ways for vegans to get saturated fat.
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