What is the ideal A1c number for a non diabetic. Mine just came back at 5.4% (out of a range of 4.5-6.0) and I thought that was a little high considering the following studies:
Association of Hemoglobin A1c with Cardiovascular Disease and Mortality in Adults: The European Prospective Investigation into Cancer in Norfolk. Kay-Tee Khaw, MBBChir FRCP; Nicholas Wareham, MBBS, FRCP; Sheila Bingham, PhD; Robert Luben, BSc; Ailsa Welch, BSc; and Nicholas Day, PhD. Annals of Internal Medicine, 9/21/2004, Vol 141, no 6, 413-420 http://annals.org/article.aspx?volume=1 ... 6&page=413
Here's the summary from that paper's conclusions:
In men and women, the relationship between hemoglobin A1c and cardiovascular disease (806 events) and between hemoglobin A1c and all-cause mortality (521 deaths) was continuous and significant throughout the whole distribution. The relationship was apparent in persons without known diabetes. Persons with hemoglobin A1c concentrations less than 5% had the lowest rates of cardiovascular disease and mortality. An increase in hemoglobin A1c of 1 percentage point was associated with a relative risk for death from any cause of 1.24 (95% CI, 1.14 to 1.34; P < 0.001) in men and with a relative risk of 1.28 (CI, 1.06 to 1.32; P < 0.001) in women. These relative risks were independent of age, body mass index, waist-to-hip ratio, systolic blood pressure, serum cholesterol concentration, cigarette smoking, and history of cardiovascular disease.
Another study which drew similar conclusions discovered an even tighter correlation between A1c and heart disease risk that began as A1c rose above 4.6%, a level that corresponds to a blood sugar level of 86 mg/dl (4.8 mmol/l).
Glycemic Control and Coronary Heart Disease Risk in Persons With and Without Diabetes. The Atherosclerosis Risk in Communities Study. Elizabeth Selvin,et. al. Arch Intern Med. 2005;165:1910-1916. http://www.ncbi.nlm.nih.gov/pubmed/1615 ... t=Abstract
To quote what that study found:
In nondiabetic adults, HbA1c level was not related to CHD risk below a level of 4.6% but was significantly related to risk above that level (P<.001). In diabetic adults, the risk of CHD increased throughout the range of HbA1c levels. In the adjusted model, the Risk Ratio of CHD for a 1 percentage point increase in HbA1c level was 2.36 (95% CI, 1.43-3.90) in persons without diabetes but with an HbA1c level greater than 4.6%. In diabetic adults, the Risk Ratio was 1.14 (95% CI, 1.07-1.21) per 1 percentage point increase in HbA1c across the full range of HbA1c values.
With a BMI of 18.5 and exercising regularly, I'm not sure what else to do. I successfully gave up sugar about 8 weeks ago, so maybe I just need to have it tested again at a later date since I probably ate too many Mcdougall friendly sweet treats that first month and it is a test of three month values.
Any insight would be helpful!